Red Amber List C to D

Guidance in the Red / Amber List serves ONLY to define where clinical and prescribing responsibility for the listed medicines should lie in terms of governance and safety.

  • Inclusion in this list does NOT imply the medicine has been accepted for use via Managed Entry, does NOT imply endorsement of use, and does NOT take account of the cost implications of use of a particular medicine.
  • Prescribers should use this list in conjunction with guidance on the Managed entry process for medicines, and the NI formulary which includes information on current cost effective choices.
  • As far as possible, new specialist medicines are added to the list at the point when they are granted a UK product licence. In some instances this may be prior to the medicine being launched.

The table below lists specialist medicines. Users should search by generic name where possible. Brand names listed are not exhaustive.

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Approved NameExample Trade NamesContextStatusGuidanceNew Entry
C1 esterase inhibitor Cinryze, Berinert Red
Cabergoline Cabaser Amber Cabergoline Neurology Shared Care Guideline
Cabergoline Dostinex Amber Cabergoline Endocrinology Shared Care Guideline
Cabozantinib Cometriq Red
Canakinumab Ilaris Red
Cannabidiol (as Epidyolex) Lennox Gastaut syndrome or Dravet syndrome Red
Cannabis buccal mucosal spray Sativex Red
CAPD Continuous Ambulatory Peritoneal Dialysis solutions Red
Capecitabine Xeloda Red
Caplacizumab Red
Capsaicin patch Qutenza Red
Carfilzomib Kyprolis Red
Cemiplimab Libtayo Red
Ceritinib Zykadia Red
Certolizumab pegol Cimzia Red
Cetrorelix Cetrotide Red
Chenodeoxycholic acid Xenbilox Red
Chlorambucil Leukeran Red
Chloroquine Nivaquine Non-malaria indications Amber No Shared Care Guideline Required (Click for info)
Choriogonadotropin Ovitrelle Infertility Red
Chorionic gonadotrophin Choragon, Pregnyl Infertility Red
Ciclosporin Neoral Immunosuppressant post transplantation Amber Ciclosporin Post Transplant Shared Care Guideline
Ciclosporin Neoral Non transplant indications Amber Ciclosporin (Non-Transplant Indications) Shared Care Guideline
Cinacalcet Mimpara Amber Cinacalcet Shared Care Guideline
Cladribine Mavenclad Multiple sclerosis Red
Clomifene Clomid Amber Clomifene Shared Care Guideline
Clonidine ADHD and other behavioural and neurodevelopmental disorders Amber No Shared Care Guideline Required (Click for Info)
Clozapine Clozaril Red
Cobicistat Tybost Red
Cobimetinib Cotellic Red
Colistimethate sodium (Inhaled) Colomycin Amber Colistimethate Shared Care Guideline
Collagenase clostridium histolyticum Xiapex Red
Conestat alfa Ruconest Red
Crizanlizumab Adakveo Red
Crizotinib Xalkori Red
Cyclophosphamide When used as a systemic anti-cancer therapy Red
Cyclophosphamide (oral) Non-cancer indications Amber Cyclophosphamide Shared Care Guideline
Cytarabine and daunorubicin liposomal Red
Cytotoxics IV various examples Red
Dabrafenib Tafinlar Red
Daclatasvir Daklinza Red
Daclizumab Zinbryta Red
Dacomitinib Vizimpro Red
Dalteparin sodium Fragmin Amber
Dapsone Dermatology / Immunology Amber Dapsone Shared Care Guideline
Daratumumab Darzalex Red
Darbepoetin Aranesp Amber Local Arrangements For Shared Care May Apply (click for info)
Darolutamide Nubeqa Red
Darunavir Red
Darunavir + cobicistat Rezolsta Red
Darunavir + cobicistat + emtricitabine + tenofovir alafenamide Symtuza Red
Dasabuvir Exviera Red
Dasatinib Sprycel Red
Deferasirox Exjade Red
Deferiprone Ferriprox Red
Defibrotide Defitelio Red
Delamanid Deltyba Red
Demeclocycline SIADH Amber Demeclocycline Shared Care Guideline
Denosumab Prolia Osteoporosis Amber Denosumab (Prolia) Shared Care Guideline
Denosumab Xgeva Bone metastases from solid tumours; giant cell tumour of bone Red
Desferrioxamine Desferal Chronic iron overload Amber No Shared care Guideline Required (Click for info)
Desferrioxamine Desferal Treatment of iron poisoning Red
Deucravacitinib Sotyktu Red
Dexamethasone Implant Ozurdex Intravitreal injection route Red
Dexamfetamine Dexedrine Attention deficit hyperactivity disorder in adults and children 6 years and over, within NICE recommended doses, and for use in narcolepsy. Amber Dexamfetamine Shared care Guideline
Dexamfetamine Dexedrine Attention deficit hyperactivity disorder in children under 6 years, or doses over NICE recommended doses Red
Dimethyl fumarate Skilarence Psoriasis Amber Dimethyl fumarate (Skilarence) shared care guideline
Dimethyl Fumarate Tecfidera Multiple sclerosis Red
Dinutuximab Unituxin Red
Diroximel fumarate Vumerity Red
Dolutegravir Tivicay Red
Dolutegravir + abacavir + lamivudine Triumeq Red
Dolutegravir + rilpivirine Juluca Red
Doravirine Pifeltro Red
Doravirine + lamivudine + tenofovir disoproxil fumarate Delstrigo Red
Dornase alfa Pulmozyme Amber No Shared Care guideline required (Click for info)
Dostarlimab Jemperli Red
Dronedarone Multaq Amber Dronedarone Shared Care Guideline
Dupilumab Dupixent Red
Durvalumab Red
Duvelisib Copiktra Red

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